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Two New Neutrophil Subsets Define a Discriminating Sepsis Signature.

Aida Meghraoui-KheddarBenjamin G ChoustermanNoëlline GuillouSierra M BaroneSamuel GranjeaudHelene ValletAurélien CorneauKarim GuessousCharles de RoquetailladeAlexandre BoissonnasJonathan M IrishChristophe Combadière
Published in: American journal of respiratory and critical care medicine (2021)
This study showed that these two new neutrophil subsets were specific to sepsis and detectable by routine flow cytometry using seven markers. The demonstration here that a simple blood test distinguishes sepsis from other inflammatory conditions represents a key biological milestone that can be immediately translated into improvements in patient care.
Keyphrases
  • flow cytometry
  • septic shock
  • acute kidney injury
  • intensive care unit
  • peripheral blood