Nitric Oxide Modulates Ca 2+ Leak and Arrhythmias via S-Nitrosylation of CaMKII.
Amelia S PowerEsther U AsamudoLuke P I WorthingtonChidera C AlimRaquel E ParackalRachel S WallaceObialunanma V EbenebeJoan Heller BrownMark J KohrDonald M BersJeffrey R EricksonPublished in: Circulation research (2023)
-nitrosylation at cysteine-290 might worsen or sustain β-adrenergic receptor-induced arrhythmias. This has important implications for the administration of NO donors in the clinical setting.