APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study.
Francisca S RodriguezMatthias L SchroeterKatrin ArélinA Veronica WitteRonny BaberRalph BurkhardtChristoph EngelMarkus LöfflerJoachim ThieryArno VillringerTobias LuckSteffi G Riedel-HellerPublished in: Health psychology : official journal of the Division of Health Psychology, American Psychological Association (2017)
Our findings suggest that the dementia risk variant of the APOE gene does not alter the association between lifestyle factors and cognitive performance in the general population aged 40- to 79-years-old. However, as lifestyle factors impact cognitive aging, research efforts should focus on establishing effective interventions promoting healthy lifestyle behaviors to counteract adverse cognitive aging processes. (PsycINFO Database Record