Login / Signup

Identifying and ranking causal biochemical biomarkers for breast cancer: a Mendelian randomisation study.

Sonja N TangVerena ZuberKonstantinos K Tsilidis
Published in: BMC medicine (2022)
Our findings support a likely causal role of genetically predicted levels of testosterone, HDL cholesterol, and IGF-1, as well as a novel potential role of ALP in breast cancer aetiology. Further studies are needed to understand full disease pathways that may inform breast cancer prevention.
Keyphrases
  • risk assessment
  • signaling pathway
  • replacement therapy
  • cell proliferation
  • climate change
  • binding protein
  • pi k akt
  • human health