Identifying and ranking causal biochemical biomarkers for breast cancer: a Mendelian randomisation study.
Sonja N TangVerena ZuberKonstantinos K TsilidisPublished in: BMC medicine (2022)
Our findings support a likely causal role of genetically predicted levels of testosterone, HDL cholesterol, and IGF-1, as well as a novel potential role of ALP in breast cancer aetiology. Further studies are needed to understand full disease pathways that may inform breast cancer prevention.