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Is individual genetic susceptibility a link between silica exposure and development or severity of silicosis? A systematic review.

Kaio Cezar Rodrigues SalumMarcos César Santos de CastroAngela Santos Ferreira NaniFabiana Barzotto Kohlrausch
Published in: Inhalation toxicology (2020)
Regardless of the advances in the knowledge of the importance of gene variations in silicosis, more studies need to be performed, in particular, special polygenic and genome-wide investigations.
Keyphrases
  • genome wide
  • pulmonary fibrosis
  • dna methylation
  • copy number
  • healthcare
  • case control
  • gene expression
  • transcription factor