Non-Invasive Radiofrequency Hyperthermia Attenuates HMGB1/TLR4/NF-κB Inflammatory Axis in a Chronic Prostatitis/Chronic Pelvic Pain Syndrome Rat Model.
Soomin KimJun Jie PiaoSeokhwan BangHyong Woo MoonHyuk Jin ChoU Syn HaSung-Hoo HongJi Youl LeeHae Hoon KimHa Nul KimKyung-Hwa JeonMahadevan Raj RajasekaranSae Woong KimWoong Jin BaePublished in: The world journal of men's health (2024)
In conclusion, RFHT demonstrated anti-inflammatory effects by inhibiting the HMGB1-TLR4-NF-κB pathway in CP/CPPS rat models. This suggests that RFHT could serve as a safe and promising therapeutic strategy for CP/CPPS.