Evaluation of the relation between subclinical systolic dysfunction defined by four-dimensional speckle-tracking echocardiography and growth differentiation factor-15 levels in patients with acromegaly.
Busra FirlatanUgur Nadir KarakulakVedat HekimsoyBurcin Gonul Iremliİncilay LayDeniz YuceSelcuk DagdelenGiray KabakciTomris ErbasPublished in: Hormones (Athens, Greece) (2024)
Our study demonstrates that while LVEF was within normal limits, global strain parameters (GLS, GCS, GAS, and GRS) measured by using a novel imaging technique, 4DSTE, were lower in patients with acromegaly, suggesting the presence of subclinical systolic dysfunction in patients with acromegaly. GDF-15 can be a potential predictor of cardiovascular risk in patients with acromegaly.