SY-1530, a highly selective BTK inhibitor, effectively treats B-cell malignancies by blocking B-cell activation.
Liao WangYinghui SunXijie LiuHongjuan LiChang LuRonghui YangChuanzhen YangBinghui LiPublished in: Cancer biology & medicine (2021)
SY-1530 is an irreversible and selective BTK inhibitor that shows inhibitory effects on B-cell malignancies by blocking the BCR signaling pathway. Therefore, it may be a promising therapeutic approach for the treatment of B-cell malignancies.