Magnetic resonance spectroscopy reveals abnormalities of glucose metabolism in the Alzheimer's brain.
Roger J MullinsDavid ReiterDimitrios KapogiannisPublished in: Annals of clinical and translational neurology (2018)
Higher glucose to creatine ratios in the AD brain likely reflect lower glucose utilization. Our findings reveal pronounced metabolic abnormalities in the AD brain and strongly suggest that brain glucose merits further investigation as a candidate AD biomarker.