The role of interleukins in pathogenesis and prognosis of atrial fibrillation.
Mohammad Erfan LotfiParmida Sadat PezeshkiNima RezaeiPublished in: Expert review of clinical immunology (2023)
Interleukins and inflammatory markers can be used as markers of diagnosis, cardiovascular events, and mortality in AF patients. Finally, the utilization of substances upregulating IL-10, such as resolvin D1 (RvD1), or applying IL-6 down-regulators and inhibitors, including anti-IL-6 antibodies, colchicine, and C1q/tumor necrosis factor-related protein-9 (CTRP9), are effective in the reduction of atrial interstitial fibrosis and treating AF patients.
Keyphrases
- atrial fibrillation
- cardiovascular events
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- prognostic factors
- rheumatoid arthritis
- heart failure
- cardiovascular disease
- left atrial
- type diabetes
- catheter ablation
- direct oral anticoagulants
- transcription factor
- venous thromboembolism
- mitral valve
- patient reported