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Synthesis of new anticancer and anti-inflammatory isoxazolines and aziridines from the natural (-)-deltoin.

Mansour ZnatiMeriem DebbabiAnis RomdhaneHichem Ben JannetJalloul Bouajila
Published in: The Journal of pharmacy and pharmacology (2018)
Some analogues have been found more bioactive than deltoin 1. Their activity has been related to the nature of the added heterocycles. It would be interesting to evaluate their in-vivo activity.
Keyphrases
  • anti inflammatory
  • molecular docking