Molecular-based allergy diagnosis of allergic bronchopulmonary aspergillosis in Aspergillus fumigatus-sensitized Japanese patients.
H TanimotoYuma FukutomiH YasuedaY TakeuchiA SaitoK WataiK SekiyaT TsuburaiK AsanoM TaniguchiK AkiyamaPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2016)
The levels of IgE to Asp f 1 and/or Asp f 2 can effectively differentiate ABPA from Af-sensitized asthma, suggesting that the amounts of IgE specific for these molecules are markers for genuine Af-sensitization in ABPA. However, comorbid AD must be taken into consideration in the interpretation of high IgE to Asp f 6. Establishing of IgE-sensitization profiles using panel of Af-allergen components provides valuable information for distinguishing genuine vs. cross-reactive sensitization in Af-sensitized patients.