Donor germ-line variants associate with outcomes of allogeneic hematopoietic stem cell transplantation in patients with myelodysplastic syndromes.
Paul L AuerManzur FaraziTao ZhangJing DongYung-Tsi BolonStephen R SpellmanWael SaberPublished in: American journal of hematology (2024)
Overall survival probability for MDS patients who underwent allo-HCT and were matched to donors that are wild-type (red) and heterozygous (blue) for the rs111224634 SNP.
Keyphrases
- allogeneic hematopoietic stem cell transplantation
- wild type
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- acute myeloid leukemia
- acute lymphoblastic leukemia
- peritoneal dialysis
- genome wide
- patient reported outcomes
- gene expression
- skeletal muscle
- metabolic syndrome
- cell death
- cell proliferation
- cell cycle arrest