Downregulation of CYP17A1 by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties.

Maneera Y AljaberNelson N OrieAsmaa RaeesSouhail KraiemMashael Al-JaberWaseem SamsamMostafa M HamzaDavid AbrahamNorman M KnetemanAlka BeotraVidya Mohamed-AliMohammed Al Maadheed

Published in: Future science OA (2022)

downregulation without a significant increase in plasma progesterone, which has a vasodilatory effect involving inhibition of voltage-dependent calcium channels, and the potential to enhance 20-hydroxyecdysone vasorelaxation.

Keyphrases

cell proliferation
signaling pathway
estrogen receptor
human health