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Novel approach towards musculoskeletal phenotypes.

Ingebrigt MeisingsetOttar VasseljenNina K VøllestadHilde S RobinsonAstrid WoodhouseKaia B EngebretsenMari GletteCecilie K ØveråsAnne L NordstogaKari A I EvensenEivind S Skarpsno
Published in: European journal of pain (London, England) (2020)
This observational prospective study identified five distinct and clinically meaningful phenotypes based on biopsychosocial prognostic factors across common musculoskeletal pain. These phenotypes were independent of primary pain location, showed good external validity, and clear variation in treatment outcome. The findings are particularly valuable as they describe the heterogeneity of patients with musculoskeletal pain and points to a need for more targeted interventions in common musculoskeletal disorders to improve treatment outcome.
Keyphrases
  • chronic pain
  • prognostic factors
  • pain management
  • neuropathic pain
  • single cell
  • spinal cord
  • cancer therapy
  • drug delivery