Integrative, high-resolution analysis of single cells across experimental conditions with PARAFAC2.

Andrew RamirezBrian T Orcutt-JahnsSean PascoeArmaan AbrahamBreanna RemigioNathaniel ThomasAaron S Meyer

Published in: bioRxiv : the preprint server for biology (2024)

PARAFAC2 enables tensor-based analysis of single-cell experiments across conditions.PARAFAC2 separates condition-specific effects from cell-to-cell variation.PARAFAC2 provides intuitive isolation of patterns into condition-, cell-, and gene-specific patterns.

Keyphrases

single cell
rna seq
high resolution
cell therapy
high throughput
stem cells
gene expression
mass spectrometry
oxidative stress
genome wide
signaling pathway
mesenchymal stem cells
cell death
high speed