Chitosan-Rapamycin Carbon Dots Alleviate Glaucomatous Retinal Injury by Inducing Autophagy to Promote M2 Microglial Polarization.
Qi WangJiaxin DongMengxian DuXinna LiuShiqi ZhangDi ZhangWanyun QinXikun XuXianghui LiRuidong SuLeyi QiuBaoqiang LiHuiping YuanPublished in: International journal of nanomedicine (2024)
CRCD could serve as a potential novel treatment strategy for glaucoma, via incorporating RAPA into CDs, in turn not only mitigating its toxic side effects but also enhancing its therapeutic efficacy.
Keyphrases
- optic nerve
- drug delivery
- optical coherence tomography
- quantum dots
- cell death
- inflammatory response
- endoplasmic reticulum stress
- diabetic retinopathy
- signaling pathway
- sensitive detection
- lipopolysaccharide induced
- fluorescent probe
- living cells
- neuropathic pain
- wound healing
- human health
- risk assessment
- spinal cord injury
- climate change
- genome wide analysis