Exposure levels of mycophenolic acid are associated with comorbidities in children with systemic lupus erythematosus.
Qiaofeng YeGuangfei WangJinmiao LuYidie HuangJunqi ZhangLin ZhuYiqing ZhuJianger LanZiwei LiYubing LiuHong XuZhiping LiPublished in: Lupus (2021)
Increased levels of MPA exposure are associated with decreased incidence odds of diabetes, AKI or pneumonia in SLE children. An AUC0-24h of 100.39 mg · h/L or an AUC0-12h of 50.20 mg · h/L could be used as the targeted exposure level for clinical practice.