Total metabolic tumor volume and spleen metabolism on baseline [18F]-FDG PET/CT as independent prognostic biomarkers of recurrence in resected breast cancer.
Romain-David SebanRoman RouzierAurelien LatoucheNicolas DelevalJean-Marc GuinebretiereIrene BuvatFrancois-Clement BidardLaurence ChampionPublished in: European journal of nuclear medicine and molecular imaging (2021)
High total metabolic tumor volume and high spleen glucose metabolism on baseline [18F]-FDG PET/CT were associated with poor 5y-RFS after surgical resection in patients with breast cancer of NST. Spleen metabolism was inversely correlated with stromal TILs and might be a surrogate for an immunosuppressive tumor microenvironment.
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