Aging Aggravates Cachexia in Tumor-Bearing Mice.

Julia GeppertAlina A WalthRaúl Terrón ExpósitoDoris KalteneckerPauline MorignyJuliano MachadoMaike Becker Estefania Simoes Joanna D C C LimaCarolin DanielMauricio Berriel DiazStephan HerzigMarilia SeelaenderMaria Rohm

Published in: Cancers (2021)

Aging affects cachexia development and progression in mice in a strain-dependent manner and influences the inflammatory profile in both mice and patients. Age is an important factor to consider for future cachexia studies.

Keyphrases

high fat diet induced
end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
oxidative stress
prognostic factors
type diabetes
peritoneal dialysis
wild type
patient reported outcomes
skeletal muscle
case control