Endothelium-Independent Vasodilatory Effect of Sailuotong (SLT) on Rat Isolated Tail Artery.

Seung Yeon Yeon Sai-Wang SetoG H H ChanM Low Hosen KiatN WangJ LiuDennis H Chang

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

SLT induces relaxation of rat isolated tail artery through endothelium-independent mechanisms. The SLT-induced vasodilatation appeared to be jointly meditated by blockages of extracellular Ca2+ influx via receptor-gated and voltage-gated Ca2+ channels and inhibition of the release of Ca2+ from the sarcoplasmic reticulum.

Keyphrases

nitric oxide
oxidative stress
protein kinase
diabetic rats
drug induced