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Spatial biology of Ising-like synthetic genetic networks.

Kevin SimpsonAlfredo L'HommeJuan KeymerFernán Federici
Published in: BMC biology (2023)
Our findings shed light on the spatial biology of coupled and bistable gene networks in growing cell populations. This emergent spatial behavior could provide insights into the study and engineering of self-organizing gene patterns in eukaryotic tissues and bacterial consortia.
Keyphrases
  • genome wide
  • copy number
  • cell therapy
  • dna methylation
  • stem cells
  • bone marrow
  • mesenchymal stem cells