Peritoneal transformation shortly after kidney transplantation in pediatric patients with preceding chronic peritoneal dialysis.

Conghui ZhangMaria BartosovaIva MarinovicConstantin SchwabBetti SchaeferKarel VondrakGema AricetaAriane ZaloszycBruno RanchinChristina TaylanRainer BüscherJun OhArianeb MehrabiClaus Peter Schmitt

Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)

Peritoneal membrane damage induced with chronic administration of low-GDP PD fluids was less severe after KTx. While peritoneal microvessel density, primarily defining PD transport and ultrafiltration capacity, was normal after KTx and peritoneal inflammation less pronounced, diffuse podoplanin positivity and profibrotic activity were prevalent.

Keyphrases

peritoneal dialysis
end stage renal disease
oxidative stress
drug induced
diabetic rats
low grade
early onset
high grade