Spatiotemporal ATP Dynamics during AKI Predict Renal Prognosis.

Shinya YamamotoMasamichi YamamotoJin NakamuraAkiko MiiShigenori YamamotoMasahiro TakahashiKeiichi KanekoEiichiro UchinoYuki SatoShingo FukumaHiromi ImamuraMichiyuki MatsudaEiichiro Uchino

Published in: Journal of the American Society of Nephrology : JASN (2020)

Visualizing spatiotemporal ATP dynamics during IR injury revealed higher sensitivity of PT cells to ischemia compared with DT cells in terms of energy metabolism. The ATP dynamics of PTs in AKI might provide prognostic information.

Keyphrases

induced apoptosis
cell cycle arrest
acute kidney injury
endoplasmic reticulum stress
cell death
oxidative stress
signaling pathway
healthcare
health information
cell proliferation