Hypoxia directed migration of human naïve monocytes is associated with an attenuation of cytokine release: indications for a key role of CCL26.

Lars HummitzschRouven BerndMatthias KottRene RuschFred FaendrichMatthias GruenewaldMarkus SteinfathMartin AlbrechtKarina Zitta

Published in: Journal of translational medicine (2020)

Hypoxia induces directed migration of human monocytes in-vitro. Autocrine/paracrine released CCL26 is involved in the hypoxia-mediated monocyte migration and may represent a target molecule for the modulation of monocyte migration in-vivo.

Keyphrases

endothelial cells
dendritic cells
peripheral blood
liver injury
immune response
drug induced