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Anticancer effect of the antipsychotic agent penfluridol on epithelial ovarian cancer.

Won-Ji KimJi-Yoon RyuChi-Son ChangYoung-Jae ChoYoung-Jae ChoJae Ryoung HwangJu-Yeon ChoiJeong-Won Lee
Published in: Journal of gynecologic oncology (2024)
Penfluridol exerted significant anticancer effects on EOC cells and xenograft models, including PDX. Thus, penfluridol therapy, as a drug repurposing strategy, might be a potential therapeutic for EOCs.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • emergency department
  • oxidative stress
  • cell death
  • cell proliferation
  • pi k akt
  • electronic health record