Pharmacological and non-pharmacological interventions for irritability in autism spectrum disorder: a systematic review and meta-analysis with the GRADE assessment.
Hangnyoung ChoiJae Han KimHee Sang YangJong Yeob KimSamuele CorteseLee SmithAi KoyanagiElena DragiotiJoaquim RaduaPaolo Fusar-PoliJae Il ShinKeun-Ah CheonMarco SolmiPublished in: Molecular autism (2024)
Only risperidone, aripiprazole among pharmacological interventions, and parent training among non-pharmacological interventions can be recommended for irritability in ASD. As an augmentation to risperidone, several novel treatments show promising effects, but further RCTs are needed to replicate findings. Trial registration PROSPERO, CRD42021243965.