Synergistic Cytotoxic Effect from Combination of Wedelolactone and Cisplatin in HeLa Cell Line: A Novel Finding.

Sadia SarwarJun Qing YuHumaira NadeemFazlul Huq

Published in: Drug design, development and therapy (2020)

This is the first study reporting cytotoxic activity of WDL in HeLa cells either as single agent or in combination with cisplatin. These results support the idea that sequential combination of cisplatin with WDL and BA may work effectively in cervical cancer cells.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
pi k akt
emergency department
signaling pathway
adverse drug
cell proliferation
cancer therapy