Inflammation, mitochondrial dysfunction and physical performance: a possible association in older patients with persistent atrial fibrillation-the results of a preliminary study.

Stefano FumagalliGiulia RicciardiClaudia Di SerioGiancarlo La MarcaGiuseppe PieracciniRiccardo Franci MontorziEmanuele SantamariaGiulia SpanalatteFrancesca MarchettiGinevra CortiLaura PintonNiccolò Marchionni

Published in: Aging clinical and experimental research (2023)

In older AF patients, IL-6 correlated with acylcarnitines and lower physical performance. Alterations in energy production, reduced physical function and inflammation could contribute to frailty development.

Keyphrases

atrial fibrillation
physical activity
oxidative stress
end stage renal disease
mental health
ejection fraction
newly diagnosed
community dwelling
heart failure
peritoneal dialysis
left atrial
coronary artery disease
middle aged
left ventricular