Sonic hedgehog signalling as a potential endobronchial biomarker in COPD.
Julien AncelRanda BelgacemiJeanne-Marie PerotinZania DiabasanaSandra DuryMaxime DewolfArnaud BonnometNathalie LalunPhilippe BirembautMyriam PoletteGaëtan DesléeValérian DormoyPublished in: Respiratory research (2020)
This study demonstrates the feasibility of assessing HH pathway activation in respiratory samples collected by bronchoscopy and identifies impaired bronchial epithelial HH signalling in COPD.