Sonic hedgehog signalling as a potential endobronchial biomarker in COPD.

Julien AncelRanda BelgacemiJeanne-Marie PerotinZania DiabasanaSandra DuryMaxime DewolfArnaud BonnometNathalie LalunPhilippe BirembautMyriam PoletteGaëtan DesléeValérian Dormoy

Published in: Respiratory research (2020)

This study demonstrates the feasibility of assessing HH pathway activation in respiratory samples collected by bronchoscopy and identifies impaired bronchial epithelial HH signalling in COPD.

Keyphrases

chronic obstructive pulmonary disease
lung function
ultrasound guided
risk assessment
human health
dna methylation
air pollution