Genetic variation at the Th2 immune gene IL13 is associated with IgE-mediated paediatric food allergy.

Sarah E AshleyH-T T TanR PetersK J AllenP VuillerminS C DharmageM L K TangJ KoplinA LoweA-L PonsonbyJ MolloyM C MathesonR SafferyJ A EllisD Martinonull null

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2017)

We show for the first time, in two independent cohorts, that IL13 polymorphism rs1295686 (in complete linkage disequilibrium with functional variant rs20541) is associated with challenge-proven food allergy.

Keyphrases

genome wide
intensive care unit
emergency department
copy number
dna methylation
gene expression
hiv testing
hepatitis c virus
men who have sex with men
atopic dermatitis