Quantitative proteomic analysis of cerebrospinal fluid from patients with idiopathic facial nerve palsy.

Ilias MasourisM KleinB AngeleB GroßNeha GoswamiFathima MashoodManuela Gesell SalazarS SchubertH W PfisterU KoedelF Schmidt

Published in: European journal of neurology (2022)

Our study revealed a subgroup of IFP patients with elevated CSF protein that showed upregulated inflammatory pathways, suggesting an inflammatory/infectious cause. However, no evidence for an inflammatory cause was found in IFP patients with normal CSF.

Keyphrases

cerebrospinal fluid
oxidative stress
high resolution
single cell
clinical trial
mass spectrometry
soft tissue
study protocol
phase iii