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A Genomic Risk Score Identifies Individuals at High Risk for Intracerebral Hemorrhage.

Evangelos Pavlos MyserlisMarios K GeorgakisStacie L DemelPadmini SekarJaeyoon ChungRainer MalikHyacinth I HyacinthMary E ComeauGuido J FalconeCarl D LangefeldJonathan RosandDaniel WooChristopher D Anderson
Published in: Stroke (2023)
We developed and validated a genomic risk score that predicts lifetime risk of ICH beyond established clinical risk factors among individuals of European ancestry. Whether implementation of the score in risk prognostication models for high-risk populations, such as patients under antithrombotic treatment, could improve clinical decision making should be explored in future studies.
Keyphrases
  • risk factors
  • decision making
  • end stage renal disease
  • newly diagnosed
  • ejection fraction
  • healthcare
  • primary care
  • copy number
  • prognostic factors
  • brain injury
  • genome wide
  • patient reported outcomes
  • gene expression