Role of the GalNAc-galectin pathway in the healing of premature rupture of membranes.

Jia-Le ChenLou LiuXin-Rui PengYan WangXiang XiangYu ChenDe-Xiang XuDao-Zhen Chen

Published in: Molecular medicine (Cambridge, Mass.) (2024)

GalNAc might be a potential target for the prevention and treatment of PROM through the galectin pathway, including (i) inflammation; (ii) epithelial-mesenchymal transition; (iii) proliferation and migration; and (iv) regression, remodeling, and healing.

Keyphrases

epithelial mesenchymal transition
oxidative stress
transforming growth factor
signaling pathway
human health
combination therapy
replacement therapy