Central Nervous System Toxicity of Voriconazole: Risk Factors and Threshold - A Retrospective Cohort Study.

Luting YangChuhui WangYijing ZhangQuanfang WangYulan QiuSihan LiBo YangQian DuJiaojiao ChenMengmeng TengTaotao WangYa-Lin Dong

Published in: Infection and drug resistance (2022)

for CNS toxicity is 4.85mg/L. TDM should be routinely performed in patients with clinical use of voriconazole to reduce the occurrence of CNS toxicity of voriconazole.

Keyphrases

risk factors
oxidative stress
blood brain barrier
risk assessment
oxide nanoparticles
cerebrospinal fluid