Extracellular vesicular microRNAs as potential biomarker for early detection of doxorubicin-induced cardiotoxicity.

Vicky K YangSally R RobinsonNicholas RobinsonKatherine E LopezDawn M MeolaLisa G BarberBarret J BulmerJerome CalvalidoJohn E RushAshish YeriSaumya DasVicky K Yang

Published in: Journal of veterinary internal medicine (2020)

Downregulation of miR-502 was detected before significant changes in cTnI concentrations or echocardiographic parameters. Further validation using a larger sample size will be required.

Keyphrases

cell proliferation
long non coding rna
high glucose
diabetic rats
left ventricular
drug delivery
long noncoding rna
mitral valve
signaling pathway
drug induced
cancer therapy
left atrial
heart failure
ejection fraction
oxidative stress
stress induced