Modulation of LXR signaling altered the dynamic activity of human colon adenocarcinoma cancer stem cells in vitro.

Hassan Dianat-MoghadamMostafa KhaliliMohsen KeshavarzMehdi AziziHamed HamishehkarReza RahbarghaziMohammad Nouri

Published in: Cancer cell international (2021)

The regulation of LXR activity can be considered as a selective targeting of survival, metabolism, and migration in CSCs to control the tumorigenesis and metastasis in patients with advanced colorectal cancers.

Keyphrases

cancer stem cells
endothelial cells
squamous cell carcinoma
induced pluripotent stem cells
locally advanced
radiation therapy
free survival
drug delivery