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Comparative efficacy of subcutaneous versus intravenous natalizumab on annualized relapse rate: A post-hoc analysis of the REFINE study.

Alice MariottiniFabrizia MealliAlessandra MatteiLuca Massacesi
Published in: Multiple sclerosis and related disorders (2024)
NTZ-SC resulted not inferior to NTZ-IV on ARR for all the non-inferiority margins. The non-inferiority analysis of the efficacy of NTZ-SC vs NTZ-IV on CUAL was demonstrated to be robust with respect to rescued patients.
Keyphrases
  • end stage renal disease
  • multiple sclerosis
  • newly diagnosed
  • chronic kidney disease
  • ejection fraction
  • peritoneal dialysis
  • high dose
  • patient reported outcomes
  • patient reported