Preclinical evaluation of two phylogenetically distant arenavirus vectors for the development of novel immunotherapeutic combination strategies for cancer treatment.
Josipa RaguzCatarina PintoTheresa PölzlbauerMohamed HabbeddineSandra RosskopfJudith StraußValentin JustSarah SchmidtKatell Bidet HuangFelix StemesederTimo SchippersEthan StewartJakub JezPedro BerraondoKlaus K OrlingerHenning LauterbachPublished in: Journal for immunotherapy of cancer (2024)
The artARENA platform represents a strong therapeutic vaccine approach for the treatment of cancer. The induced antitumor immune response builds the backbone for novel combination therapies, which warrant further investigation.