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Visible light-induced photoredox catalyzed C-N coupling of amides with alcohols.

Shraddha TivariPravin K SinghPraveen P SinghVishal Srivastava
Published in: RSC advances (2022)
A visible-light-mediated method for the construction of N -monoalkylated products from easily available benzamides and benzyl alcohol in the presence of eosin Y has been developed. The reaction proceeded smoothly, for a wide range of derivatives of benzamides and benzyl alcohols, to give the desired products in good to excellent yields. Biological studies, such as those on drug-likeness and molecular docking, are carried out on the molecules.
Keyphrases
  • visible light
  • molecular docking
  • room temperature
  • molecular dynamics simulations
  • high glucose
  • drug induced
  • diabetic rats
  • endothelial cells
  • emergency department
  • electron transfer
  • adverse drug
  • stress induced