The role of MMP-12 gene polymorphism - 82 A-to-G (rs2276109) in immunopathology of COPD in polish patients: a case control study.

Iwona GilowskaEdyta MajorczykŁukasz KasperKatarzyna BogaczJan SzczegielniakMarta KasperJacek KaczmarskiAleksandra SkomudekMarcin CzerwinskiKrzysztof Sładek

Published in: BMC medical genetics (2019)

We found that -82G allele of SNP rs2276109 was associated with reduced risk of COPD, and COPD patients released more MMP-12 than healthy individuals, but independently on this SNP.

Keyphrases

end stage renal disease
chronic obstructive pulmonary disease
ejection fraction
chronic kidney disease
newly diagnosed
lung function
peritoneal dialysis
genome wide
gene expression
patient reported outcomes
cystic fibrosis
patient reported
high density