Trend of blood donors entering the coronavirus pandemic era and challenges: Age-period-cohort analysis using 75.5 million all blood donations data during 2006-2020 in Japan.

The number of blood donations in 2020 increased despite COVID-19 and it proved that the blood donation promotion was effective. The different age-specific blood donation rates between our study and the report of BD research group infers the effect of COVID-19 on blood donation were differed by age and suggested the need for different approaches to blood donation promotion by generation.