Although with intact mucosa at colonoscopy, chagasic megacolons have an overexpression of Gal-3.

Mariana Pacífico Garvil Taíssa Cássia de Souza Furtado Natália Biagioni de Lima Maria Vitória Mattar Marteleto Juliana Barbosa de Faria Denise Bertulucci Rocha Rodrigues Sanívia Aparecida de Lima Pereira

Published in: Einstein (Sao Paulo, Brazil) (2020)

The higher density of anti-galectin-3-immunostained cells in patients in the chagasic patients with intact mucosa group suggested the need for greater attention in clinical evaluation of these patients, since this protein is associated with neoplastic transformation and progression.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
transcription factor
patient reported outcomes
signaling pathway
endoplasmic reticulum stress
binding protein
cell cycle arrest
protein protein
pi k akt