Tablets or oral suspension for posaconazole in lung transplant recipients? Consequences for trough concentrations of tacrolimus and everolimus.

Sébastien ChanoineElodie Gautier-VeyretHélène PluchartJulia ToniniXavier FonroseJohanna ClaustrePierrick BedouchFrançoise Stanke-Labesque

Published in: British journal of clinical pharmacology (2020)

The greater PCZ exposure achieved during PCZ-tab treatment increased drug-drug interactions with TAC and EVR, resulting in greater exposure, potentially exposing patients to higher risks of adverse effects.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
emergency department
drug induced
replacement therapy