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Insulin sensitivity and kinetics in African American and White people with obesity: Insights from different study protocols.

Han-Chow E KohBruce W PattersonDominic N ReedsBettina Mittendorfer
Published in: Obesity (Silver Spring, Md.) (2022)
AA individuals are not more insulin resistant than NHW individuals, and the β-cell response to glucose ingestion and postprandial insulin clearance are not different between AA individuals and NHW individuals. However, AA individuals have greater insulin secretory capacity and reduced insulin clearance capacity than NHW individuals and might be susceptible to hyperinsulinemia after consuming very large amounts of glucose.
Keyphrases
  • type diabetes
  • african american
  • glycemic control
  • blood glucose
  • metabolic syndrome
  • insulin resistance
  • stem cells
  • weight loss
  • adipose tissue
  • mesenchymal stem cells
  • physical activity
  • bone marrow