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HBV S antigen evolution in the backdrop of HDV infection affects epitope processing and presentation.

Mehwish SajjadSyed AliSamina BaigShaheen SharafatBilal Ahmed KhanSaeed KhanNouman MughalSyed Hani Abidi
Published in: Journal of medical virology (2020)
These observations suggest that HBV selectively amplifies certain mutations in the backdrop of HDV coinfection. Selective amplification of these mutations at certain strategic locations might not only enable HBV to counteract the inhibitory effects of HDV on HBV replication but also facilitate its survival by escaping the immune response.
Keyphrases
  • hepatitis b virus
  • liver failure
  • immune response
  • dendritic cells
  • toll like receptor
  • case report
  • inflammatory response
  • monoclonal antibody