High-grade glioma in infants and very young children: characteristics, treatment, and outcomes.

Omar ArafahEslam MaherAmal MosaabEman NaguibAmal RefaatSoha AhmedHala TahaMohamed El-BeltagyMoatasem El-Ayadi

Published in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2024)

This study in a large cohort of HGG in infants and very young children offers insights into the characteristics and treatment challenges. Extent of resection, age group, and tumor localization are important prognostic factors. Further research with larger sample size is warranted to refine treatment approaches and improve outcomes.

Keyphrases

high grade
prognostic factors
combination therapy
low grade
replacement therapy
weight loss
smoking cessation