Glucocorticoid treatment in patients with complex regional pain syndrome: A systematic review.
Corinne van den BergPim N de BreeFrank J P M HuygenJitske TiemensmaPublished in: European journal of pain (London, England) (2022)
Several studies point towards CRPS being an inflammatory response after tissue or nerve damage, with higher levels of pro-inflammatory cytokines in serum, plasma, cerebrospinal fluid and artificial skin blisters. Inflammation provides a possible role for glucocorticoids in treating CRPS. This systematic review provides a structured overview of glucocorticoid treatment in patients with CRPS. Improvement in pain and range of motion is shown. Systematic review registration number: PROSPERO-CRD42020144671.