Diagnostic accuracy in field conditions of the sickle SCAN® rapid test for sickle cell disease among children and adults in two West African settings: the DREPATEST study.
Akueté Yvon SegbenaAldiouma GuindoRomain BuonoIrénée KueviakoeDapa A DialloGregory GuernecMouhoudine YerimaPierre GuindoEmilie LauresserguesAude MondeilhValentina PicotValériane LeroyPublished in: BMC hematology (2018)
Rapid POC testing is 100% accurate for homozygote healthy people and excellent (Togo) or perfect (Mali) for sickle cell trait and disease patients. In addition to its comparable diagnostic performance, this test is cheaper, easier to implement, and logistically more convenient than the current standard diagnostic methods in use. Its predictive value indicators and diagnostic accuracy in newborns should be further evaluated prior to implementation in large-scale screening programs in resource-limited settings where SCD is prevalent.
Keyphrases
- sickle cell disease
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- pregnant women
- healthcare
- computed tomography
- primary care
- peritoneal dialysis
- public health
- prognostic factors
- genome wide
- loop mediated isothermal amplification
- quality improvement
- patient reported
- gestational age
- low birth weight