Risk Factors for Severe Cutaneous Anthrax in a Retrospective Case Series and Use of a Clinical Algorithm to Identify Likely Meningitis and Evaluate Treatment Outcomes, Kyrgyz Republic, 2005-2012.
Ainura KutmanovaSaparbai ZholdoshevKatherine M RoguskiMelis Sholpanbay UuluMarissa K PersonRachel CookJulia BugryshevaPatrick NadolAisuluu BuranchievaLira ImanbaevaAinura DzhangazievaWilliam A BowerKatherine HendricksPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)
Based on our analyses, treatment of anthrax meningitis may not require 3 antimicrobials, which could impact future anthrax treatment recommendations. In addition, chronic comorbidities may increase risk for severe anthrax and anthrax meningitis. Future research should further investigate potential risk factors for severe anthrax and their impact on laboratory-confirmed meningitis and evaluate mono- and dual-therapy antimicrobial regimens for anthrax meningitis.